¿POR QUÉ? ¿POR QUÉ? ¿POR QUÉ?...

Alessandro Pungitopo formula en un mensaje de Facebook la siguiente pregunta: ¿Por qué los ataques contra la teoría del Dr. Zamboni?. Al leerlo no pude evitar acordarme del video colgado en Youtube incrustado arriba. Un nota de humor nunca viene mal. Para aquellos que nos leen desde fuera de España y no sean aficcionados al futbol, decirles que el protagonista del video es José Mourinho, entrenador del Real Madrid. Traduzco el mensaje de Alessandro:

Continuan los ataques fuera de lugar en contra de la teoría del Dr. Zamboni sobre la posible correlación entre la CCSVI, que descubrió en 2007, y la esclerosis múltiple (EM), enfermedad gravemente debilitante que afecta a unos 63.000 italianos y para la cual no hay todavía una terapia definitiva. Se presentan en orden cronológico descendente una serie de estudios publicados el año pasado en las revistas científicas que demuestran que la teoría del Dr. Zamboni no es una ficción, como algunos nos quieren hacer creer. Los que siguen negando la existencia y prevalencia de la CCSVI entre los pacientes con esclerosis múltiple, demuestran tener pocos conocimientos científicos y, sobre todo, ignorancia de la literatura reciente.

J Vasc Surg. 2012 Apr 20. [Epub ahead of print] Assessment of cerebral venous return by a novel plethysmography method. Zamboni P, Menegatti E, Conforti P, Shepherd S, Tessari M, Beggs C. http://www.ncbi.nlm.nih.gov/pubmed/22521804

AJNR Am J Neuroradiol. 2012 Apr 19. [Epub ahead of print] Extracranial Venous Drainage Patterns in Patients with Multiple Sclerosis and Healthy Controls. McTaggart RA, Fischbein NJ, Elkins CJ, Hsiao A, Cutalo MJ, Rosenberg J, Dake MD, Zaharchuk G. http://www.ncbi.nlm.nih.gov/pubmed/22517280

Vasc Med. 2012 Apr 10. [Epub ahead of print] Endovascular correction of cerebrovenous anomalies in Multiple Sclerosis: A retrospective review of an uncontrolled case series. Dake MD, Dantzker N, Bennett WL, Cooke JP. http://www.ncbi.nlm.nih.gov/pubmed/22496109

Curr Neurovasc Res. 2012 Apr 4. [Epub ahead of print] Multigate Quality Doppler Profiles and Morphological/Hemodynamic Alterations in Multiple Sclerosis Patients. Ciccone MM, Galeandro AI, Scicchitano P, Zito A, Gesualdo M, Sassara M, Cortese F, Dachille A, Carbonara R, Federico F, Livrea P, Trojano M. http://www.ncbi.nlm.nih.gov/pubmed/22475396

Radiology. 2012 Mar;262(3):947-55. Multiple sclerosis: cerebral circulation time. Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M. http://www.ncbi.nlm.nih.gov/pubmed/22357894

EuroRad (2012, Mar 5). Ultrasonic evaluation of internal jugular veins in multiple sclerosis. Oreste D, Pavone S http://www.eurorad.org/case.php?id=9897

Phlebology. 2012 Feb 22. [Epub ahead of print] Neck duplex Doppler ultrasound evaluation for assessing chronic cerebrospinal venous insufficiency in multiple sclerosis patients. Zaniewski M, Kostecki J, Kuczmik W, Ziaja D, Opala G, Swiat M, Korzeniowski T, Majewski E, Urbanek T, Pawlicki K. http://www.ncbi.nlm.nih.gov/pubmed/22357458

J Vasc Interv Radiol. 2012 Jan;23(1):60-8.e1-3. Patients with multiple sclerosis with structural venous abnormalities on MR imaging exhibit an abnormal flow distribution of the internal jugular veins. Haacke EM, Feng W, Utriainen D, Trifan G, Wu Z, Latif Z, Katkuri Y, Hewett J, Hubbard D. http://www.ncbi.nlm.nih.gov/pubmed/22221473

Funct Neurol. 2011 Oct-Dec;26(4):197-203. Prevalence of extracranial venous abnormalities: results from a sample of 586 multiple sclerosis patients. Simka M, Latacz P, Ludyga T, Kazibudzki M, Swierad M, Janas P, Piegza J. http://www.ncbi.nlm.nih.gov/pubmed/22364940

J Vasc Interv Radiol. 2012 Jan;23(1):55-9. Epub 2011 Nov 15. Safety of endovascular treatment of chronic cerebrospinal venous insufficiency: a report of 240 patients with multiple sclerosis. Mandato KD, Hegener PF, Siskin GP, Haskal ZJ, Englander MJ, Garla S, Mitchell N, Reutzel L, Doti C. http://www.ncbi.nlm.nih.gov/pubmed/22088659

BMC Neurol. 2011 Oct 26;11:132. Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study. Bastianello S, Romani A, Viselner G, Tibaldi EC, Giugni E, Altieri M, Cecconi P, Mendozzi L, Farina M, Mariani D, Galassi A, Quattrini C, Mancini M, Bresciamorra V, Lagace A, McDonald S, Bono G, Bergamaschi R. http://www.ncbi.nlm.nih.gov/pubmed/22029656

BMC Neurol. 2011 Oct 19;11:128. Decreased brain venous vasculature visibility on susceptibility-weighted imaging venography in patients with multiple sclerosis is related to chronic cerebrospinal venous insufficiency. Zivadinov R, Poloni GU, Marr K, Schirda CV, Magnano CR, Carl E, Bergsland N, Hojnacki D, Kennedy C, Beggs CB, Dwyer MG, Weinstock-Guttman B. http://www.ncbi.nlm.nih.gov/pubmed/22011402

CMAJ. 2011 Nov 8;183(16):E1203-12. Epub 2011 Oct 3. Association between chronic cerebrospinal venous insufficiency and multiple sclerosis: a meta-analysis. Laupacis A, Lillie E, Dueck A, Straus S, Perrier L, Burton JM, Aviv R, Thorpe K, Feasby T, Spears J. http://www.ncbi.nlm.nih.gov/pubmed/21969411

Georgian Med News. 2011 Oct;(199):29-34. Endovascular treatment of patients with chronic cerebrospinal venous insufficiency and multiple sclerosis. Kipshidze N, Rukhadze I, Archvadze A, Kipiani V, Kipshidze N, Lapiashvili E, Kaloiani V. http://www.ncbi.nlm.nih.gov/pubmed/22155803

Phlebology. 2011 Sep 8. [Epub ahead of print] Morphological and haemodynamic abnormalities in the jugular veins of patients with multiple sclerosis. Radak D, Kolar J, Tanaskovic S, Sagic D, Antonic Z, Mitrasinovic A, Babic S, Nenezic D, Ilijevski N. http://www.ncbi.nlm.nih.gov/pubmed/21903685

Acta Phlebologica 2011 August;12(2):109-13 Venous extracranial Duplex ultrasound and possible correlations between multiple sclerosis and CCSVI: an observational study after 560 exams Bavera P. M., Mendozzi L., Cavarretta R., Agus G.B. http://www.minervamedica.it/en/journals/acta-phlebologica/article.php?cod=R43Y2011N02A0109

Eur J Vasc Endovasc Surg. 2012 Jan;43(1):116-22. Epub 2011 Aug 11. Venous angioplasty in patients with multiple sclerosis: results of a pilot study. Zamboni P, Galeotti R, Weinstock-Guttman B, Kennedy C, Salvi F, Zivadinov R. http://www.ncbi.nlm.nih.gov/pubmed/21839654

J Endovasc Ther. 2011 Jun;18(3):314-23. Safety profile of endovascular treatment for chronic cerebrospinal venous insufficiency in patients with multiple sclerosis. Petrov I, Grozdinski L, Kaninski G, Iliev N, Iloska M, Radev A. http://www.ncbi.nlm.nih.gov/pubmed/21679067

J Neurol Neurosurg Psychiatry 28 April 2011 Anatomical stenosis of the internal jugular veins : supportive evidence of chronic cerebrospinal venous insufficiency? Andrea Baiocchini, MD Raffaele Toscano, Wilfredo von Lorch and Franca Del Nonno http://jnnp.bmj.com/content/82/4/355.extract/reply#jnnp_el_7244

Phlebological Review 2011; 19(1):9-14 Early results of a prospective open-label study on endovascular treatments for chronic cerebrospinal venous insufficiency in the patients with associated multiple sclerosis Tomasz Ludyga, Marek Kazibudzki, Paweł Latacz, Marcin Świerad, Jacek Piegza, Marcin Hartel, Ewa Kluczewska, Marian Simka http://journals.indexcopernicus.com/abstracted.php?level=5&icid=935588

Phlebology. 2010 Dec;25(6):286-95. Endovascular treatment for chronic cerebrospinal venous insufficiency: is the procedure safe? Ludyga T, Kazibudzki M, Simka M, Hartel M, Swierad M, Piegza J, Latacz P, Sedlak L, Tochowicz M. http://www.ncbi.nlm.nih.gov/pubmed/21107001